HCSGD entry for SEMA6A


1. General information

Official gene symbolSEMA6A
Entrez ID57556
Gene full namesema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Other gene symbolsHT018 SEMA SEMA6A1 SEMAQ VIA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001764Neuron migrationIEAbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0004888Transmembrane signaling receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006915Apoptotic processNASbiological_process
GO:0007010Cytoskeleton organizationNASbiological_process
GO:0007166Cell surface receptor signaling pathwayNASbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007399Nervous system developmentNASbiological_process
GO:0007411Axon guidanceNAS TASbiological_process
GO:0009887Organ morphogenesisNASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0030215Semaphorin receptor bindingIEAmolecular_function
GO:0030424AxonNAScellular_component
GO:0051642Centrosome localizationIEAbiological_process
GO:0071526Semaphorin-plexin signaling pathwayIEAbiological_process
GO:2001224Positive regulation of neuron migrationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52167251240.18264474750.99999024730.8282895245

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0345098097
GSE13712_SHEARDown-0.4430404553
GSE13712_STATICDown-0.2202233029
GSE19018Down-0.2193850320
GSE19899_A1Down-0.0087452800
GSE19899_A2Up0.0885865219
PubMed_21979375_A1Down-0.0647163576
PubMed_21979375_A2Up0.0258554821
GSE35957Up0.0246575319
GSE36640Up2.6317313198
GSE54402Up0.0881524455
GSE9593Down-0.0245886889
GSE43922Down-1.4133603976
GSE24585Down-0.1930977214
GSE37065Up0.5512180846
GSE28863_A1Down-0.1703768691
GSE28863_A2Down-0.4072898306
GSE28863_A3Up0.1881830581
GSE28863_A4Up0.0861619778
GSE48662Up0.1189205333

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30c-5pMIMAT0000244MIRT047836CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.