HCSGD entry for NLGN2

1. General information

Official gene symbolNLGN2
Entrez ID57555
Gene full nameneuroligin 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002087Regulation of respiratory gaseous exchange by neurological system processISSbiological_process
GO:0004872Receptor activityIBAmolecular_function
GO:0005887Integral component of plasma membraneIBA ISScellular_component
GO:0007158Neuron cell-cell adhesionISSbiological_process
GO:0007416Synapse assemblyIBA ISS NASbiological_process
GO:0009986Cell surfaceIBA ISScellular_component
GO:0016020MembraneNAScellular_component
GO:0016337Cell-cell adhesionNASbiological_process
GO:0019233Sensory perception of painIEAbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0032230Positive regulation of synaptic transmission, GABAergicISSbiological_process
GO:0035418Protein localization to synapseISSbiological_process
GO:0035641Locomotory exploration behaviorIEAbiological_process
GO:0042043Neurexin family protein bindingIBA ISS NASmolecular_function
GO:0042734Presynaptic membraneIEAcellular_component
GO:0045202SynapseIBA ISScellular_component
GO:0045211Postsynaptic membraneNAScellular_component
GO:0045217Cell-cell junction maintenanceNASbiological_process
GO:0050804Regulation of synaptic transmissionISSbiological_process
GO:0050808Synapse organizationISSbiological_process
GO:0050839Cell adhesion molecule bindingISSmolecular_function
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051965Positive regulation of synapse assemblyISSbiological_process
GO:0051968Positive regulation of synaptic transmission, glutamatergicISSbiological_process
GO:0060077Inhibitory synapseISScellular_component
GO:0072553Terminal button organizationISSbiological_process
GO:0097104Postsynaptic membrane assemblyISSbiological_process
GO:0097105Presynaptic membrane assemblyISSbiological_process
GO:0097116Gephyrin clusteringISSbiological_process
GO:0097119Postsynaptic density protein 95 clusteringISSbiological_process
GO:0097151Positive regulation of inhibitory postsynaptic membrane potentialISSbiological_process
GO:2000311Regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityISSbiological_process
GO:2000463Positive regulation of excitatory postsynaptic membrane potentialISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39364820870.63672788270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1540579987
GSE13712_SHEARDown-0.2880463845
GSE13712_STATICDown-0.2348257134
GSE19018Up0.2506569505
GSE19899_A1Up0.0266862187
GSE19899_A2Up0.0810641968
PubMed_21979375_A1Down-0.3448037518
PubMed_21979375_A2Up0.3184083416
GSE35957Up0.0029041179
GSE36640Up0.3443752921
GSE54402Down-0.0233089272
GSE9593Up0.0508754991
GSE43922Down-0.0007348265
GSE24585Up0.0660472400
GSE37065Up0.0093208478
GSE28863_A1Up0.3783692571
GSE28863_A2Up0.0705982663
GSE28863_A3Up0.0717450348
GSE28863_A4Down-0.0942900672
GSE48662Up0.2876452464

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-378a-3pMIMAT0000732MIRT043911CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.