HCSGD entry for NCEH1
1. General information
| Official gene symbol | NCEH1 |
|---|---|
| Entrez ID | 57552 |
| Gene full name | neutral cholesterol ester hydrolase 1 |
| Other gene symbols | AADACL1 NCEH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IEA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0017171 | Serine hydrolase activity | IEA | molecular_function |
| GO:0042301 | Phosphate ion binding | IEA | molecular_function |
| GO:0052689 | Carboxylic ester hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0168003609 | 0.4651593101 | 0.3202044171 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0908882714 |
| GSE13712_SHEAR | Up | 0.9516299824 |
| GSE13712_STATIC | Up | 0.6585746182 |
| GSE19018 | Up | 0.3501185719 |
| GSE19899_A1 | Up | 0.3302395574 |
| GSE19899_A2 | Up | 0.2884345416 |
| PubMed_21979375_A1 | Down | -0.2292305719 |
| PubMed_21979375_A2 | Down | -0.0963436915 |
| GSE35957 | Down | -0.3711825092 |
| GSE36640 | Up | 0.1181360406 |
| GSE54402 | Down | -0.5489034631 |
| GSE9593 | Up | 1.0573895655 |
| GSE43922 | Up | 0.2915623765 |
| GSE24585 | Up | 0.9145079291 |
| GSE37065 | Up | 0.5812097296 |
| GSE28863_A1 | Down | -0.3727943640 |
| GSE28863_A2 | Up | 0.4992573714 |
| GSE28863_A3 | Down | -0.5430395195 |
| GSE28863_A4 | Up | 0.1017259277 |
| GSE48662 | Down | -0.8533458812 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005151 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT020097 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024804 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025849 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026590 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037667 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
