HCSGD entry for PTK7
1. General information
| Official gene symbol | PTK7 |
|---|---|
| Entrez ID | 5754 |
| Gene full name | protein tyrosine kinase 7 |
| Other gene symbols | CCK-4 CCK4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001736 | Establishment of planar polarity | IEA | biological_process |
| GO:0001843 | Neural tube closure | IEA | biological_process |
| GO:0003401 | Axis elongation | IEA | biological_process |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004714 | Transmembrane receptor protein tyrosine kinase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IDA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0010976 | Positive regulation of neuron projection development | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016477 | Cell migration | IMP | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
| GO:0031532 | Actin cytoskeleton reorganization | IMP | biological_process |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0045198 | Establishment of epithelial cell apical/basal polarity | IEA | biological_process |
| GO:0060026 | Convergent extension | IEA | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | IMP | biological_process |
| GO:0060484 | Lung-associated mesenchyme development | IEA | biological_process |
| GO:0071300 | Cellular response to retinoic acid | IMP | biological_process |
| GO:0090103 | Cochlea morphogenesis | IEA | biological_process |
| GO:0090179 | Planar cell polarity pathway involved in neural tube closure | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9954124767 | 0.0007403632 | 0.9999902473 | 0.0512818421 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2839788455 |
| GSE13712_SHEAR | Down | -1.0008640586 |
| GSE13712_STATIC | Down | -0.4075524958 |
| GSE19018 | Up | 0.0883764217 |
| GSE19899_A1 | Down | -0.4398285791 |
| GSE19899_A2 | Down | -2.0762659069 |
| PubMed_21979375_A1 | Down | -1.0795022226 |
| PubMed_21979375_A2 | Down | -1.8561606678 |
| GSE35957 | Down | -0.1761937792 |
| GSE36640 | Down | -0.5059923498 |
| GSE54402 | Down | -0.6872113919 |
| GSE9593 | Down | -0.1575903440 |
| GSE43922 | Down | -1.5427354259 |
| GSE24585 | Down | -0.2022877012 |
| GSE37065 | Down | -0.5918227048 |
| GSE28863_A1 | Up | 0.0277183477 |
| GSE28863_A2 | Down | -0.1543006666 |
| GSE28863_A3 | Down | -0.0554165085 |
| GSE28863_A4 | Down | -0.6594505371 |
| GSE48662 | Up | 0.3001354910 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023149 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025958 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041454 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043228 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049679 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
