HCSGD entry for SRGAP1
1. General information
| Official gene symbol | SRGAP1 |
|---|---|
| Entrez ID | 57522 |
| Gene full name | SLIT-ROBO Rho GTPase activating protein 1 |
| Other gene symbols | ARHGAP13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005100 | Rho GTPase activator activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0007266 | Rho protein signal transduction | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0016477 | Cell migration | IEA | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3139696136 | 0.0793857908 | 0.9999902473 | 0.5323601019 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0349383941 |
| GSE13712_SHEAR | Up | 0.2685714705 |
| GSE13712_STATIC | Up | 0.3196919386 |
| GSE19018 | Down | -0.2439769534 |
| GSE19899_A1 | Down | -0.5067694470 |
| GSE19899_A2 | Down | -0.6587302797 |
| PubMed_21979375_A1 | Down | -1.0178420827 |
| PubMed_21979375_A2 | Down | -0.2405006607 |
| GSE35957 | Up | 0.4430947511 |
| GSE36640 | Down | -0.7321496775 |
| GSE54402 | Down | -0.5267500363 |
| GSE9593 | Up | 0.2516930364 |
| GSE43922 | Down | -0.3980056085 |
| GSE24585 | Up | 0.0140275059 |
| GSE37065 | Down | -0.0862095483 |
| GSE28863_A1 | Up | 0.7891492096 |
| GSE28863_A2 | Up | 0.2678063364 |
| GSE28863_A3 | Up | 0.0338508481 |
| GSE28863_A4 | Down | -0.0108670209 |
| GSE48662 | Up | 0.8201769056 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT005810 | In situ hybridization//Luciferase reporter assay//qRT-PCR//western blot | Functional MTI | 21276775 |
| hsa-miR-214-3p | MIMAT0000271 | MIRT005811 | In situ hybridization//Luciferase reporter assay//qRT-PCR//western blot | Functional MTI | 21276775 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018618 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023976 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037552 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-5p | MIMAT0004792 | MIRT037797 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
