HCSGD entry for RPTOR

1. General information

Official gene symbolRPTOR
Entrez ID57521
Gene full nameregulatory associated protein of MTOR, complex 1
Other gene symbolsKOG1 Mip1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001030RNA polymerase III type 1 promoter DNA bindingIDAmolecular_function
GO:0001031RNA polymerase III type 2 promoter DNA bindingIDAmolecular_function
GO:0001032RNA polymerase III type 3 promoter DNA bindingIDAmolecular_function
GO:0001156TFIIIC-class transcription factor bindingIDAmolecular_function
GO:0001938Positive regulation of endothelial cell proliferationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007050Cell cycle arrestTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008361Regulation of cell sizeIMPbiological_process
GO:0016049Cell growthIMPbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0031669Cellular response to nutrient levelsIMPbiological_process
GO:0031929TOR signalingIDA IEAbiological_process
GO:0031931TORC1 complexIDA IEAcellular_component
GO:0032008Positive regulation of TOR signalingIDAbiological_process
GO:0032403Protein complex bindingIPImolecular_function
GO:0045945Positive regulation of transcription from RNA polymerase III promoterIMPbiological_process
GO:0071230Cellular response to amino acid stimulusIMPbiological_process
GO:007188914-3-3 protein bindingIDA IEAmolecular_function
GO:0071902Positive regulation of protein serine/threonine kinase activityIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09051787930.93611401160.63286417951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0986817771
GSE13712_SHEARUp0.2753175651
GSE13712_STATICUp0.4770639883
GSE19018Down-0.1614963139
GSE19899_A1Up0.0511278084
GSE19899_A2Up0.3653425712
PubMed_21979375_A1Up0.7979867001
PubMed_21979375_A2Up0.6516781063
GSE35957Down-0.1883011964
GSE36640Down-0.1210039342
GSE54402Down-0.0824785404
GSE9593Up0.0123982188
GSE43922Up0.0353978276
GSE24585Up0.1307697945
GSE37065Down-0.0731811888
GSE28863_A1Up0.2772893344
GSE28863_A2Up0.2084900383
GSE28863_A3Up0.1294611891
GSE28863_A4Up0.0567201121
GSE48662Up0.1175159948

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-27b-3pMIMAT0000419MIRT046186CLASHFunctional MTI (Weak)23622248
hsa-miR-27a-3pMIMAT0000084MIRT050023CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-99a-5pMIMAT00000971hsa-miR-99a20484036
hsa-miR-100-5pMIMAT00000981hsa-miR-100{Western blot}{knock down}20484036
Entries Per Page
Displaying Page of

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.