HCSGD entry for INTS2
1. General information
| Official gene symbol | INTS2 |
|---|---|
| Entrez ID | 57508 |
| Gene full name | integrator complex subunit 2 |
| Other gene symbols | INT2 KIAA1287 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016180 | SnRNA processing | IDA IEA | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0032039 | Integrator complex | IDA IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2210626876 | 0.0688591619 | 0.9026100481 | 0.4952027322 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2632032017 |
| GSE13712_SHEAR | Up | 0.9738867972 |
| GSE13712_STATIC | Up | 0.8344063288 |
| GSE19018 | Down | -0.2566568513 |
| GSE19899_A1 | Down | -0.3684881177 |
| GSE19899_A2 | Up | 0.1295687373 |
| PubMed_21979375_A1 | Down | -0.5026891443 |
| PubMed_21979375_A2 | Down | -0.5396263160 |
| GSE35957 | Down | -0.9879427928 |
| GSE36640 | Down | -0.3294568502 |
| GSE54402 | Down | -0.2690681919 |
| GSE9593 | Down | -0.2037627293 |
| GSE43922 | Up | 0.0961226815 |
| GSE24585 | Up | 0.2711216550 |
| GSE37065 | Up | 0.2947045421 |
| GSE28863_A1 | Down | -0.0203354409 |
| GSE28863_A2 | Up | 0.5388900624 |
| GSE28863_A3 | Down | -0.9563318918 |
| GSE28863_A4 | Up | 0.1812091257 |
| GSE48662 | Down | -0.1955520177 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021883 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-28-3p | MIMAT0004502 | MIRT038945 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047608 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
