HCSGD entry for HEG1
1. General information
| Official gene symbol | HEG1 |
|---|---|
| Entrez ID | 57493 |
| Gene full name | heart development protein with EGF-like domains 1 |
| Other gene symbols | HEG MST112 MSTP112 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001570 | Vasculogenesis | IEA | biological_process |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0001886 | Endothelial cell morphogenesis | IEA | biological_process |
| GO:0001945 | Lymph vessel development | IEA | biological_process |
| GO:0003017 | Lymph circulation | IEA | biological_process |
| GO:0003209 | Cardiac atrium morphogenesis | IEA | biological_process |
| GO:0003281 | Ventricular septum development | IEA | biological_process |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | IEA | cellular_component |
| GO:0009791 | Post-embryonic development | IEA | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030324 | Lung development | IEA | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0045216 | Cell-cell junction organization | IEA | biological_process |
| GO:0048845 | Venous blood vessel morphogenesis | IEA | biological_process |
| GO:0050878 | Regulation of body fluid levels | IEA | biological_process |
| GO:0060039 | Pericardium development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2253827286 | 0.0008567798 | 0.9068369901 | 0.0558200495 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -2.0513768689 |
| GSE13712_SHEAR | Down | -0.5245451240 |
| GSE13712_STATIC | Down | -0.0935887609 |
| GSE19018 | Down | -0.3205544665 |
| GSE19899_A1 | Down | -2.2257101251 |
| GSE19899_A2 | Down | -1.8339392826 |
| PubMed_21979375_A1 | Down | -3.6905308988 |
| PubMed_21979375_A2 | Down | -1.9282638446 |
| GSE35957 | Up | 0.8978085084 |
| GSE36640 | Up | 0.6259338777 |
| GSE54402 | Down | -1.9919487840 |
| GSE9593 | Up | 1.6399099205 |
| GSE43922 | Down | -1.5908640496 |
| GSE24585 | Up | 0.1030687831 |
| GSE37065 | Up | 0.1265959435 |
| GSE28863_A1 | Up | 0.4267124374 |
| GSE28863_A2 | Up | 0.9894179334 |
| GSE28863_A3 | Up | 0.1671105305 |
| GSE28863_A4 | Down | -0.3625928695 |
| GSE48662 | Down | -0.3603793618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020310 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027725 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028175 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031232 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
