HCSGD entry for PLEKHG1
1. General information
| Official gene symbol | PLEKHG1 |
|---|---|
| Entrez ID | 57480 |
| Gene full name | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| Other gene symbols | ARHGEF41 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0649233198 | 0.4487657232 | 0.5491152635 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5142104976 |
| GSE13712_SHEAR | Up | 1.0897561358 |
| GSE13712_STATIC | Up | 0.3278340536 |
| GSE19018 | Up | 0.0317455960 |
| GSE19899_A1 | Down | -0.0084534064 |
| GSE19899_A2 | Down | -0.2705737398 |
| PubMed_21979375_A1 | Down | -0.2110007521 |
| PubMed_21979375_A2 | Up | 0.0751777115 |
| GSE35957 | Down | -0.0345676955 |
| GSE36640 | Up | 0.0112930837 |
| GSE54402 | Down | -0.9607574538 |
| GSE9593 | Down | -0.0876200563 |
| GSE43922 | Up | 0.0050151692 |
| GSE24585 | Down | -0.2821632258 |
| GSE37065 | Down | -0.0624460361 |
| GSE28863_A1 | Up | 0.8774036580 |
| GSE28863_A2 | Up | 1.2260067824 |
| GSE28863_A3 | Up | 0.1329193306 |
| GSE28863_A4 | Up | 0.0043179210 |
| GSE48662 | Up | 0.0558071369 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016820 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
