HCSGD entry for BIRC6

1. General information

Official gene symbolBIRC6
Entrez ID57448
Gene full namebaculoviral IAP repeat containing 6
Other gene symbolsAPOLLON BRUCE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000922Spindle poleIDAcellular_component
GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0004869Cysteine-type endopeptidase inhibitor activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005768EndosomeIDAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005802Trans-Golgi networkIDAcellular_component
GO:0005815Microtubule organizing centerIDAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0010951Negative regulation of endopeptidase activityIMPbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016567Protein ubiquitinationTASbiological_process
GO:0030496MidbodyIDAcellular_component
GO:0032465Regulation of cytokinesisIMPbiological_process
GO:0042127Regulation of cell proliferationTASbiological_process
GO:0043066Negative regulation of apoptotic processIMP TASbiological_process
GO:0052548Regulation of endopeptidase activityIMPbiological_process
GO:0060711Labyrinthine layer developmentIEAbiological_process
GO:0060712Spongiotrophoblast layer developmentIEAbiological_process
GO:2001237Negative regulation of extrinsic apoptotic signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07311487410.31253549640.57601215211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5995517664
GSE13712_SHEARUp0.3547141000
GSE13712_STATICUp0.1483335760
GSE19018Up0.2084752972
GSE19899_A1Up0.3875805639
GSE19899_A2Up0.2622685067
PubMed_21979375_A1Up0.0059095394
PubMed_21979375_A2Up0.5293704147
GSE35957Up0.1565546926
GSE36640Up0.3375973221
GSE54402Up0.1239406140
GSE9593Up0.0223921299
GSE43922Down-0.0467591067
GSE24585Down-0.3945381383
GSE37065Down-0.0247989543
GSE28863_A1Up0.7012151085
GSE28863_A2Up1.1161477206
GSE28863_A3Down-0.7201411891
GSE28863_A4Down-0.3384152264
GSE48662Down-0.0480378788

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT004956qRT-PCRFunctional MTI (Weak)17942906
hsa-miR-218-5pMIMAT0000275MIRT005001Luciferase reporter assay//qRT-PCRNon-Functional MTI19890957
hsa-miR-615-3pMIMAT0003283MIRT039908CLASHFunctional MTI (Weak)23622248
hsa-miR-34a-5pMIMAT0000255MIRT047374CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052603CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.