HCSGD entry for RAB22A


1. General information

Official gene symbolRAB22A
Entrez ID57403
Gene full nameRAB22A, member RAS oncogene family
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIEAcellular_component
GO:0003924GTPase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005769Early endosomeIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006897EndocytosisIDAbiological_process
GO:0007032Endosome organizationIEPbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0019003GDP bindingIDAmolecular_function
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0045335Phagocytic vesicleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03192617680.95105649480.41273521611.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7418954735
GSE13712_SHEARDown-0.1291481743
GSE13712_STATICDown-0.0250324152
GSE19018Down-0.0179289139
GSE19899_A1Up0.3779367199
GSE19899_A2Up0.4400719809
PubMed_21979375_A1Down-0.3047696668
PubMed_21979375_A2Up0.8043328916
GSE35957Up0.1608395039
GSE36640Up0.6253506953
GSE54402Up0.2691846408
GSE9593Up0.7702373541
GSE43922Down-0.0498689291
GSE24585Up0.1784964933
GSE37065Up0.0227967300
GSE28863_A1Up0.0377311093
GSE28863_A2Up0.1845673077
GSE28863_A3Down-0.4070483093
GSE28863_A4Up0.1782464683
GSE48662Up0.1928634979

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-211-5pMIMAT0000268MIRT006465Immunofluorescence//Microarray//qRT-PCR//Western blotFunctional MTI22523078
hsa-miR-204-5pMIMAT0000265MIRT005840Luciferase reporter assay//Microarray//qRT-PCRFunctional MTI21282569
hsa-miR-204-5pMIMAT0000265MIRT005840Immunofluorescence//Microarray//qRT-PCR//Western blotFunctional MTI22523078
hsa-miR-21-5pMIMAT0000076MIRT030782MicroarrayFunctional MTI (Weak)18591254
hsa-miR-128-3pMIMAT0000424MIRT045852CLASHFunctional MTI (Weak)23622248
hsa-miR-30b-5pMIMAT0000420MIRT046136CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.