HCSGD entry for PBXIP1
1. General information
| Official gene symbol | PBXIP1 |
|---|---|
| Entrez ID | 57326 |
| Gene full name | pre-B-cell leukemia homeobox interacting protein 1 |
| Other gene symbols | HPIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003714 | Transcription corepressor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | NAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007275 | Multicellular organismal development | NAS | biological_process |
| GO:0030154 | Cell differentiation | NAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0366009080 | 0.6734486190 | 0.4341471384 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0006645012 |
| GSE13712_SHEAR | Down | -0.5091261538 |
| GSE13712_STATIC | Down | -0.2070472467 |
| GSE19018 | Up | 0.6235532746 |
| GSE19899_A1 | Up | 0.1559779069 |
| GSE19899_A2 | Up | 0.2991971953 |
| PubMed_21979375_A1 | Down | -0.6483141887 |
| PubMed_21979375_A2 | Up | 0.1106065642 |
| GSE35957 | Up | 0.2944054508 |
| GSE36640 | Up | 1.8602141090 |
| GSE54402 | Down | -0.7825343129 |
| GSE9593 | Up | 0.4084481127 |
| GSE43922 | Up | 0.1211588408 |
| GSE24585 | Up | 0.5957299101 |
| GSE37065 | Up | 0.0542114573 |
| GSE28863_A1 | Up | 0.1092694247 |
| GSE28863_A2 | Up | 0.1096800080 |
| GSE28863_A3 | Up | 0.0409297841 |
| GSE28863_A4 | Down | -0.1870595630 |
| GSE48662 | Up | 0.6554465157 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017972 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-375 | MIMAT0000728 | MIRT019795 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020198 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT026000 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028003 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029484 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038457 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050607 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050995 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
