HCSGD entry for PTGER2

1. General information

Official gene symbolPTGER2
Entrez ID5732
Gene full nameprostaglandin E receptor 2 (subtype EP2), 53kDa
Other gene symbolsEP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004957Prostaglandin E receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEA ISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0071380Cellular response to prostaglandin E stimulusIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96945355420.00002394290.99999024730.0085554054

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2047235146
GSE13712_SHEARDown-0.0595097376
GSE13712_STATICDown-0.1143303875
GSE19018Down-0.9400072328
GSE19899_A1Down-2.6348109566
GSE19899_A2Down-4.8792798899
PubMed_21979375_A1Down-5.2635725966
PubMed_21979375_A2Down-6.1807868521
GSE35957Down-2.2868033241
GSE36640Down-4.0132884993
GSE54402Down-2.5786083062
GSE9593Up0.0850842579
GSE43922Down-2.5626397883
GSE24585Down-0.1281268843
GSE37065Up1.1042467972
GSE28863_A1Down-0.2506927697
GSE28863_A2Up0.1134874019
GSE28863_A3Down-0.0898960267
GSE28863_A4Down-0.0719811686
GSE48662Down-0.6431318106

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MisoprostolDB00929 APRD00037

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019383MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.