HCSGD entry for PTGDS
1. General information
| Official gene symbol | PTGDS |
|---|---|
| Entrez ID | 5730 |
| Gene full name | prostaglandin D2 synthase 21kDa (brain) |
| Other gene symbols | L-PGDS LPGDS PDS PGD2 PGDS PGDS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001516 | Prostaglandin biosynthetic process | IDA ISS | biological_process |
| GO:0004667 | Prostaglandin-D synthase activity | IDA ISS | molecular_function |
| GO:0005215 | Transporter activity | IEA ISS | molecular_function |
| GO:0005501 | Retinoid binding | ISS | molecular_function |
| GO:0005504 | Fatty acid binding | IDA | molecular_function |
| GO:0005576 | Extracellular region | IDA IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005791 | Rough endoplasmic reticulum | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0006810 | Transport | ISS | biological_process |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019371 | Cyclooxygenase pathway | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0036094 | Small molecule binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045187 | Regulation of circadian sleep/wake cycle, sleep | ISS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2887865013 | 0.0700347099 | 0.9868702997 | 0.4997492954 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0407895251 |
| GSE13712_SHEAR | Down | -1.1189164645 |
| GSE13712_STATIC | Down | -0.0156248425 |
| GSE19018 | Down | -0.4706188933 |
| GSE19899_A1 | Down | -0.0717753299 |
| GSE19899_A2 | Down | -0.7973183334 |
| PubMed_21979375_A1 | Down | -0.0897798463 |
| PubMed_21979375_A2 | Down | -0.9005057870 |
| GSE35957 | Down | -0.6971852951 |
| GSE36640 | Up | 0.0572529994 |
| GSE54402 | Down | -0.1295603726 |
| GSE9593 | Up | 1.6708627248 |
| GSE43922 | Up | 0.0686143705 |
| GSE24585 | Up | 0.0833448827 |
| GSE37065 | Down | -0.0728797299 |
| GSE28863_A1 | Down | -0.1208059375 |
| GSE28863_A2 | Up | 0.0759187254 |
| GSE28863_A3 | Up | 0.4576987619 |
| GSE28863_A4 | Up | 0.1290975987 |
| GSE48662 | Up | 0.7241695078 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017585 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
