HCSGD entry for PSPH
1. General information
| Official gene symbol | PSPH |
|---|---|
| Entrez ID | 5723 |
| Gene full name | phosphoserine phosphatase |
| Other gene symbols | PSP PSPHD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004647 | Phosphoserine phosphatase activity | IDA IEA TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006563 | L-serine metabolic process | IDA | biological_process |
| GO:0006564 | L-serine biosynthetic process | IBA IEA TAS | biological_process |
| GO:0008652 | Cellular amino acid biosynthetic process | TAS | biological_process |
| GO:0009612 | Response to mechanical stimulus | IEA | biological_process |
| GO:0016311 | Dephosphorylation | IDA TAS | biological_process |
| GO:0031667 | Response to nutrient levels | IEA | biological_process |
| GO:0033574 | Response to testosterone | IEA | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8937085179 | 0.0478915467 | 0.9999902473 | 0.4099222475 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1162097477 |
| GSE13712_SHEAR | Up | 0.3278649230 |
| GSE13712_STATIC | Up | 0.1805570012 |
| GSE19018 | Up | 0.0214033153 |
| GSE19899_A1 | Down | -0.6548704593 |
| GSE19899_A2 | Down | -0.1298327714 |
| PubMed_21979375_A1 | Down | -0.0655743142 |
| PubMed_21979375_A2 | Down | -0.9658317515 |
| GSE35957 | Down | -0.7468302843 |
| GSE36640 | Down | -0.3689468811 |
| GSE54402 | Down | -0.3070611074 |
| GSE9593 | Down | -0.0251986233 |
| GSE43922 | Down | -0.3967758995 |
| GSE24585 | Up | 0.2152063540 |
| GSE37065 | Down | -0.4197378648 |
| GSE28863_A1 | Up | 0.0879009336 |
| GSE28863_A2 | Up | 0.0316080888 |
| GSE28863_A3 | Up | 0.0100124734 |
| GSE28863_A4 | Down | -0.1658160765 |
| GSE48662 | Up | 0.1163017754 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| D-2-Amino-3-Phosphono-Propionic Acid | DB03292 | EXPT00542 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023338 | Proteomics | Functional MTI (Weak) | 21750653 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032012 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038375 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
