HCSGD entry for VANGL2

1. General information

Official gene symbolVANGL2
Entrez ID57216
Gene full nameVANGL planar cell polarity protein 2
Other gene symbolsLPP1 LTAP STB1 STBM STBM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001736Establishment of planar polarityISSbiological_process
GO:0001843Neural tube closureISSbiological_process
GO:0001942Hair follicle developmentIEAbiological_process
GO:0001947Heart loopingISSbiological_process
GO:0003149Membranous septum morphogenesisIEAbiological_process
GO:0003150Muscular septum morphogenesisIEAbiological_process
GO:0003402Planar cell polarity pathway involved in axis elongationIEAbiological_process
GO:0005911Cell-cell junctionISScellular_component
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0016328Lateral plasma membraneISScellular_component
GO:0022007Convergent extension involved in neural plate elongationIEAbiological_process
GO:0032835Glomerulus developmentIEAbiological_process
GO:0032956Regulation of actin cytoskeleton organizationIEAbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0035058Nonmotile primary cilium assemblyISSbiological_process
GO:0035787Cell migration involved in kidney developmentISSbiological_process
GO:0036342Post-anal tail morphogenesisIEAbiological_process
GO:0042060Wound healingIEAbiological_process
GO:0043507Positive regulation of JUN kinase activityIEAbiological_process
GO:0045176Apical protein localizationISSbiological_process
GO:0045197Establishment or maintenance of epithelial cell apical/basal polarityIEAbiological_process
GO:0048103Somatic stem cell divisionIEAbiological_process
GO:0048105Establishment of body hair planar orientationIEAbiological_process
GO:0048546Digestive tract morphogenesisIEAbiological_process
GO:0060028Convergent extension involved in axis elongationIEAbiological_process
GO:0060122Inner ear receptor stereocilium organizationIEAbiological_process
GO:0060187Cell poleIEAcellular_component
GO:0060488Orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesisIEAbiological_process
GO:0060489Planar dichotomous subdivision of terminal units involved in lung branching morphogenesisIEAbiological_process
GO:0060490Lateral sprouting involved in lung morphogenesisIEAbiological_process
GO:0060993Kidney morphogenesisIEAbiological_process
GO:0090103Cochlea morphogenesisIEAbiological_process
GO:0090177Establishment of planar polarity involved in neural tube closureIEAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98932646180.00665376700.99999024730.1641603561

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5142601106
GSE13712_SHEARUp0.0590100338
GSE13712_STATICUp0.1541182903
GSE19018Down-0.8766853188
GSE19899_A1Down-0.2057615818
GSE19899_A2Down-1.0766939558
PubMed_21979375_A1Down-1.4195644574
PubMed_21979375_A2Down-0.9280901150
GSE35957Down-0.2040080847
GSE36640Down-3.3495090611
GSE54402Down-0.9810573571
GSE9593Down-0.2648145192
GSE43922Up0.0229144321
GSE24585Up0.1038687756
GSE37065Down-0.1460312944
GSE28863_A1Down-0.1842955615
GSE28863_A2Up0.0243774720
GSE28863_A3Up0.2073822827
GSE28863_A4Up0.0297886434
GSE48662Up0.0337336361

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017700MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029478SequencingFunctional MTI (Weak)20371350
hsa-miR-92a-3pMIMAT0000092MIRT049626CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.