HCSGD entry for ATP8B2
1. General information
| Official gene symbol | ATP8B2 |
|---|---|
| Entrez ID | 57198 |
| Gene full name | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| Other gene symbols | ATPID |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004012 | Phospholipid-translocating ATPase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | RCA | biological_process |
| GO:0008152 | Metabolic process | RCA | biological_process |
| GO:0016021 | Integral component of membrane | RCA | cellular_component |
| GO:0016887 | ATPase activity | RCA | molecular_function |
| GO:0019829 | Cation-transporting ATPase activity | IEA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4035339577 | 0.0383607576 | 0.9999902473 | 0.3685012774 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1372084486 |
| GSE13712_SHEAR | Down | -0.4116410303 |
| GSE13712_STATIC | Down | -0.3620333768 |
| GSE19018 | Down | -0.5882416248 |
| GSE19899_A1 | Down | -0.8013570643 |
| GSE19899_A2 | Down | -0.6259511103 |
| PubMed_21979375_A1 | Down | -0.8262900522 |
| PubMed_21979375_A2 | Down | -0.6221210578 |
| GSE35957 | Up | 0.0442413451 |
| GSE36640 | Up | 0.4891326938 |
| GSE54402 | Down | -0.0205533756 |
| GSE9593 | Up | 0.4202664065 |
| GSE43922 | Down | -0.3489846570 |
| GSE24585 | Up | 0.1900321252 |
| GSE37065 | Up | 0.0100102516 |
| GSE28863_A1 | Up | 0.5217965740 |
| GSE28863_A2 | Up | 0.5601804609 |
| GSE28863_A3 | Down | -0.6370340697 |
| GSE28863_A4 | Down | -0.3443581925 |
| GSE48662 | Up | 0.8733381004 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017239 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022360 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040979 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042625 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043377 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050479 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
