HCSGD entry for MCOLN1

1. General information

Official gene symbolMCOLN1
Entrez ID57192
Gene full namemucolipin 1
Other gene symbolsMG-2 ML4 MLIV MST080 TRP-ML1 TRPM-L1 TRPML1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005261Cation channel activityNASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006812Cation transportNASbiological_process
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0031902Late endosome membraneIEAcellular_component
GO:0033572Transferrin transportTASbiological_process
GO:0034220Ion transmembrane transportNASbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0051209Release of sequestered calcium ion into cytosolIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0072345NAADP-sensitive calcium-release channel activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00022417080.99757369020.04338529411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.4017468150
GSE13712_SHEARUp0.3113234120
GSE13712_STATICUp0.5038162745
GSE19018Up0.2593692760
GSE19899_A1Up1.1697730117
GSE19899_A2Up1.6832465622
PubMed_21979375_A1Up2.1759183410
PubMed_21979375_A2Up2.8584506610
GSE35957Up0.3050545937
GSE36640Up1.2009733240
GSE54402Up0.6368777626
GSE9593Up1.0811178532
GSE43922Up0.9457359573
GSE24585Up0.2975682315
GSE37065Up0.1605213605
GSE28863_A1Down-0.3695466312
GSE28863_A2Up0.1899863142
GSE28863_A3Up0.0794243930
GSE28863_A4Down-0.0971730014
GSE48662Up0.5447049704

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.