HCSGD entry for PSMD13


1. General information

Official gene symbolPSMD13
Entrez ID5719
Gene full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Other gene symbolsHSPC027 Rpn9 S11 p40.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000502Proteasome complexTAScellular_component
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005838Proteasome regulatory particleIEAcellular_component
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0007127Meiosis IIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0022624Proteasome accessory complexISScellular_component
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11303372210.77222290570.69235763151.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3364383269
GSE13712_SHEARDown-0.0811769768
GSE13712_STATICUp0.0445506452
GSE19018Up0.0803695995
GSE19899_A1Up0.3251292711
GSE19899_A2Up0.2299270313
PubMed_21979375_A1Up0.0610030927
PubMed_21979375_A2Down-0.0218015999
GSE35957Down-0.2385415265
GSE36640Up0.0347405251
GSE54402Up0.5490066824
GSE9593Down-0.2703320447
GSE43922Up0.3180833136
GSE24585Down-0.1008008932
GSE37065Down-0.1488204256
GSE28863_A1Up0.1743266567
GSE28863_A2Down-0.2857054369
GSE28863_A3Up0.6219298007
GSE28863_A4Down-0.1787255727
GSE48662Down-0.0423939053

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-93-3pMIMAT0004509MIRT038884CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040064CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045260CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047134CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047503CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047716CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.