HCSGD entry for VARS2

1. General information

Official gene symbolVARS2
Entrez ID57176
Gene full namevalyl-tRNA synthetase 2, mitochondrial
Other gene symbolsG7a VARS2L VARSL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002161Aminoacyl-tRNA editing activityIEAmolecular_function
GO:0004832Valine-tRNA ligase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006438Valyl-tRNA aminoacylationIEAbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79261863530.30766651340.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1057035711
GSE13712_SHEARDown-0.2346549290
GSE13712_STATICUp0.0429962258
GSE19018Up0.1926277747
GSE19899_A1Down-0.1232722367
GSE19899_A2Up0.1928683216
PubMed_21979375_A1Down-0.2360910007
PubMed_21979375_A2Up0.3194335558
GSE35957Down-0.3279802597
GSE36640Down-0.2590510879
GSE54402Down-0.0584231997
GSE9593Down-0.5930709063
GSE43922Up0.0338329935
GSE24585Down-0.2114296322
GSE37065Down-0.0745185667
GSE28863_A1Up0.0428293984
GSE28863_A2Up0.0911384436
GSE28863_A3Up0.0630835055
GSE28863_A4Down-0.0678006578
GSE48662Down-0.0372620065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.