HCSGD entry for GJC2


1. General information

Official gene symbolGJC2
Entrez ID57165
Gene full namegap junction protein, gamma 2, 47kDa
Other gene symbolsCX46.6 Cx47 GJA12 HLD2 LMPH1C PMLDAR SPG44
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005243Gap junction channel activityIEAmolecular_function
GO:0005922Connexon complexIEAcellular_component
GO:0007267Cell-cell signalingIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0009636Response to toxic substanceIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0043209Myelin sheathIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60421067590.74522128340.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0273540409
GSE13712_SHEARDown-0.2048981017
GSE13712_STATICDown-0.1601761813
GSE19018Up0.0590446637
GSE19899_A1Down-0.0516532517
GSE19899_A2Up0.1394842515
PubMed_21979375_A1Down-0.0857799106
PubMed_21979375_A2Down-0.0704094041
GSE35957Up0.0001938620
GSE36640Up0.0278958029
GSE54402Down-0.0068860798
GSE9593Up0.0701467114
GSE43922Up0.1034683407
GSE24585Up0.0509455506
GSE37065Down-0.0716187089
GSE28863_A1Down-0.1875753154
GSE28863_A2Down-0.0088116289
GSE28863_A3Up0.5264326693
GSE28863_A4Up0.0018404499
GSE48662Up0.4048336038

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-346MIMAT0000773MIRT004225MicroarrayFunctional MTI (Weak)16822819
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.