HCSGD entry for PELI2
1. General information
| Official gene symbol | PELI2 |
|---|---|
| Entrez ID | 57161 |
| Gene full name | pellino E3 ubiquitin protein ligase family member 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001934 | Positive regulation of protein phosphorylation | IDA | biological_process |
| GO:0002224 | Toll-like receptor signaling pathway | TAS | biological_process |
| GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008063 | Toll signaling pathway | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0034134 | Toll-like receptor 2 signaling pathway | TAS | biological_process |
| GO:0034142 | Toll-like receptor 4 signaling pathway | TAS | biological_process |
| GO:0034146 | Toll-like receptor 5 signaling pathway | TAS | biological_process |
| GO:0034162 | Toll-like receptor 9 signaling pathway | TAS | biological_process |
| GO:0034166 | Toll-like receptor 10 signaling pathway | TAS | biological_process |
| GO:0038123 | Toll-like receptor TLR1:TLR2 signaling pathway | TAS | biological_process |
| GO:0038124 | Toll-like receptor TLR6:TLR2 signaling pathway | TAS | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | TAS | biological_process |
| GO:0043410 | Positive regulation of MAPK cascade | IDA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9310138255 | 0.0067767562 | 0.9999902473 | 0.1645488930 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1563170104 |
| GSE13712_SHEAR | Down | -2.2156702781 |
| GSE13712_STATIC | Down | -1.0944489678 |
| GSE19018 | Down | -0.1996768548 |
| GSE19899_A1 | Down | -0.0995400878 |
| GSE19899_A2 | Down | -1.0540039575 |
| PubMed_21979375_A1 | Down | -1.3993865789 |
| PubMed_21979375_A2 | Down | -0.6080070219 |
| GSE35957 | Down | -0.1159115655 |
| GSE36640 | Down | -2.0696901485 |
| GSE54402 | Down | -0.0156945055 |
| GSE9593 | Up | 0.1298994804 |
| GSE43922 | Down | -0.0831903435 |
| GSE24585 | Up | 0.1136339255 |
| GSE37065 | Up | 0.0986505417 |
| GSE28863_A1 | Up | 0.7021501152 |
| GSE28863_A2 | Up | 0.0624377788 |
| GSE28863_A3 | Up | 0.2130315820 |
| GSE28863_A4 | Down | -0.0514088093 |
| GSE48662 | Down | -0.5461507615 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019058 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-151a-5p | MIMAT0004697 | MIRT019524 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046700 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
