HCSGD entry for CD248
1. General information
| Official gene symbol | CD248 |
|---|---|
| Entrez ID | 57124 |
| Gene full name | CD248 molecule, endosialin |
| Other gene symbols | CD164L1 TEM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016477 | Cell migration | IEA | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0048535 | Lymph node development | IEA | biological_process |
| GO:0050840 | Extracellular matrix binding | IEA | molecular_function |
| GO:0060033 | Anatomical structure regression | IEA | biological_process |
| GO:2000353 | Positive regulation of endothelial cell apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2517979940 | 0.1097374074 | 0.9415474506 | 0.6343262846 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0975486931 |
| GSE13712_SHEAR | Up | 0.0170170482 |
| GSE13712_STATIC | Down | -0.1975365269 |
| GSE19018 | Down | -0.0614116492 |
| GSE19899_A1 | Down | -0.1308536589 |
| GSE19899_A2 | Down | -0.1533399187 |
| PubMed_21979375_A1 | Down | -0.6353855072 |
| PubMed_21979375_A2 | Up | 0.6236045580 |
| GSE35957 | Up | 0.0806021161 |
| GSE36640 | Up | 0.0313512476 |
| GSE54402 | Down | -0.9458233082 |
| GSE9593 | Up | 0.0800898993 |
| GSE43922 | Down | -0.5021004749 |
| GSE24585 | Up | 0.1092167365 |
| GSE37065 | Down | -0.5150523628 |
| GSE28863_A1 | Up | 0.6227593717 |
| GSE28863_A2 | Up | 0.2178894420 |
| GSE28863_A3 | Up | 0.2574333138 |
| GSE28863_A4 | Up | 0.1625140095 |
| GSE48662 | Up | 0.0817171443 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029660 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 16010436 | Interestingly, HUV-ST cells over-express the tumor endothelial marker-1/endosialin which is regarded as the most differentially expressed molecule in tumor-derived endothelium versus normal-derived endothelium |
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