HCSGD entry for PGLYRP4

1. General information

Official gene symbolPGLYRP4
Entrez ID57115
Gene full namepeptidoglycan recognition protein 4
Other gene symbolsPGLYRPIbeta PGRP-Ibeta PGRPIB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002221Pattern recognition receptor signaling pathwayIDAbiological_process
GO:0005576Extracellular regionIEAcellular_component
GO:0005622IntracellularNAScellular_component
GO:0007165Signal transductionIDAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008745N-acetylmuramoyl-L-alanine amidase activityIEAmolecular_function
GO:0009253Peptidoglycan catabolic processIEAbiological_process
GO:0016019Peptidoglycan receptor activityIDAmolecular_function
GO:0016020MembraneNAScellular_component
GO:0016045Detection of bacteriumIDAbiological_process
GO:0032689Negative regulation of interferon-gamma productionIEAbiological_process
GO:0032827Negative regulation of natural killer cell differentiation involved in immune responseIEAbiological_process
GO:0042834Peptidoglycan bindingIDAmolecular_function
GO:0044117Growth of symbiont in hostIEAbiological_process
GO:0045087Innate immune responseNASbiological_process
GO:0050830Defense response to Gram-positive bacteriumIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55200560770.80363258990.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0431845345
GSE13712_SHEARDown-0.1630648724
GSE13712_STATICUp0.0934261971
GSE19018Up0.0019992349
GSE19899_A1Up0.0419167773
GSE19899_A2Down-0.0837249240
PubMed_21979375_A1Down-0.0227023474
PubMed_21979375_A2Up0.0144864785
GSE35957Up0.3612002031
GSE36640Up0.1439370178
GSE54402Down-0.0822030939
GSE9593Up0.0617455788
GSE43922Up0.0773536924
GSE24585Up0.1459999788
GSE37065Down-0.0175158033
GSE28863_A1Down-0.2066178013
GSE28863_A2Down-0.0894232937
GSE28863_A3Up0.2380781738
GSE28863_A4Up0.1255384379
GSE48662Up0.0768047772

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.