HCSGD entry for CYSLTR2
1. General information
| Official gene symbol | CYSLTR2 |
|---|---|
| Entrez ID | 57105 |
| Gene full name | cysteinyl leukotriene receptor 2 |
| Other gene symbols | CYSLT2 CYSLT2R HG57 HPN321 KPG_011 hGPCR21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001631 | Cysteinyl leukotriene receptor activity | IEA | molecular_function |
| GO:0004974 | Leukotriene receptor activity | NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0010942 | Positive regulation of cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0045766 | Positive regulation of angiogenesis | IEA | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6613142928 | 0.7347599293 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0636807017 |
| GSE13712_SHEAR | Down | -0.0432191650 |
| GSE13712_STATIC | Up | 0.2507582090 |
| GSE19018 | Up | 0.0222800279 |
| GSE19899_A1 | Up | 0.1670175955 |
| GSE19899_A2 | Up | 0.0584246991 |
| PubMed_21979375_A1 | Down | -0.0854579213 |
| PubMed_21979375_A2 | Down | -0.0351030429 |
| GSE35957 | Up | 0.4128309405 |
| GSE36640 | Up | 0.0642338391 |
| GSE54402 | Down | -0.1376790081 |
| GSE9593 | Up | 0.0732202223 |
| GSE43922 | Up | 0.0216926083 |
| GSE24585 | Down | -0.0084157463 |
| GSE37065 | Down | -0.0606135903 |
| GSE28863_A1 | Down | -0.0975225464 |
| GSE28863_A2 | Down | -0.1476089262 |
| GSE28863_A3 | Up | 0.1370118205 |
| GSE28863_A4 | Up | 0.0449898824 |
| GSE48662 | Down | -0.0672972616 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Nedocromil | DB00716 | APRD01137 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
