HCSGD entry for AVEN
1. General information
| Official gene symbol | AVEN |
|---|---|
| Entrez ID | 57099 |
| Gene full name | apoptosis, caspase activation inhibitor |
| Other gene symbols | PDCD12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7382202082 | 0.1082033395 | 0.9999902473 | 0.6291132951 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9710011608 |
| GSE13712_SHEAR | Up | 0.2746691481 |
| GSE13712_STATIC | Down | -0.0588868365 |
| GSE19018 | Down | -0.0836516136 |
| GSE19899_A1 | Down | -0.4814018020 |
| GSE19899_A2 | Up | 0.0867634114 |
| PubMed_21979375_A1 | Down | -0.0696893102 |
| PubMed_21979375_A2 | Down | -0.2609471661 |
| GSE35957 | Up | 0.1868635498 |
| GSE36640 | Down | -0.2512242475 |
| GSE54402 | Up | 0.1779888890 |
| GSE9593 | Up | 0.2613964761 |
| GSE43922 | Down | -0.0215375210 |
| GSE24585 | Down | -0.0214069544 |
| GSE37065 | Down | -0.0745914359 |
| GSE28863_A1 | Down | -0.1096914131 |
| GSE28863_A2 | Down | -0.0946583377 |
| GSE28863_A3 | Up | 0.2600005170 |
| GSE28863_A4 | Up | 0.1060728582 |
| GSE48662 | Down | -0.5001805863 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT007276 | Luciferase reporter assay | Functional MTI | 23445407 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022196 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027461 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
