HCSGD entry for PLSCR4
1. General information
| Official gene symbol | PLSCR4 |
|---|---|
| Entrez ID | 57088 |
| Gene full name | phospholipid scramblase 4 |
| Other gene symbols | TRA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006810 | Transport | NAS | biological_process |
| GO:0006869 | Lipid transport | NAS | biological_process |
| GO:0015914 | Phospholipid transport | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017121 | Phospholipid scrambling | NAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0017128 | Phospholipid scramblase activity | NAS | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0042609 | CD4 receptor binding | IPI | molecular_function |
| GO:0071222 | Cellular response to lipopolysaccharide | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0414111242 | 0.0182892671 | 0.4558687578 | 0.2644154860 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3756447753 |
| GSE13712_SHEAR | Up | 0.1653714534 |
| GSE13712_STATIC | Up | 0.4125849252 |
| GSE19018 | Down | -0.0276821431 |
| GSE19899_A1 | Down | -0.4644769168 |
| GSE19899_A2 | Down | -0.5431113739 |
| PubMed_21979375_A1 | Down | -2.0167496290 |
| PubMed_21979375_A2 | Down | -2.2355713310 |
| GSE35957 | Up | 0.7441786806 |
| GSE36640 | Up | 1.5435640646 |
| GSE54402 | Down | -0.9461801179 |
| GSE9593 | Up | 1.0389941778 |
| GSE43922 | Down | -0.3149595072 |
| GSE24585 | Up | 1.2443405194 |
| GSE37065 | Down | -0.0593951612 |
| GSE28863_A1 | Up | 0.9676870773 |
| GSE28863_A2 | Up | 0.7771667984 |
| GSE28863_A3 | Down | -0.4360098089 |
| GSE28863_A4 | Down | -0.4131788438 |
| GSE48662 | Down | -0.1189032606 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017393 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022441 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027128 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031585 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046398 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
