HCSGD entry for CHRNA10
1. General information
| Official gene symbol | CHRNA10 |
|---|---|
| Entrez ID | 57053 |
| Gene full name | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004889 | Acetylcholine-activated cation-selective channel activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005230 | Extracellular ligand-gated ion channel activity | IEA | molecular_function |
| GO:0005262 | Calcium channel activity | IEA | molecular_function |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IGI | biological_process |
| GO:0007271 | Synaptic transmission, cholinergic | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0042127 | Regulation of cell proliferation | TAS | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043204 | Perikaryon | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0050910 | Detection of mechanical stimulus involved in sensory perception of sound | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6249653775 | 0.7679817256 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0698284677 |
| GSE13712_SHEAR | Down | -0.0700517518 |
| GSE13712_STATIC | Up | 0.0491451571 |
| GSE19018 | Up | 0.1126462054 |
| GSE19899_A1 | Up | 0.0091732902 |
| GSE19899_A2 | Up | 0.2161044390 |
| PubMed_21979375_A1 | Down | -0.0191766560 |
| PubMed_21979375_A2 | Up | 0.0415477088 |
| GSE35957 | Up | 0.0814861724 |
| GSE36640 | Up | 0.0595399842 |
| GSE54402 | Up | 0.0543862944 |
| GSE9593 | Up | 0.1569397750 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.3670302417 |
| GSE28863_A2 | Up | 0.0836285750 |
| GSE28863_A3 | Up | 0.1533840687 |
| GSE28863_A4 | Up | 0.0989830948 |
| GSE48662 | Down | -0.1574738072 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Nicotine | DB00184 | APRD00200 | EXPT02315 | DB09463 |
| Succinylcholine | DB00202 | APRD00159 |
| Methadone | DB00333 | APRD00485 |
| Galantamine | DB00674 | APRD00206 | EXPT01628 |
| Pentolinium | DB01090 | APRD00038 |
| Trimethaphan | DB01116 | APRD00044 |
| Chloroprocaine | DB01161 | APRD00404 |
| ATG003 | DB05069 | - |
| Lobeline | DB05137 | - |
| RPI-78M | DB05740 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
