HCSGD entry for CCNL1
1. General information
| Official gene symbol | CCNL1 |
|---|---|
| Entrez ID | 57018 |
| Gene full name | cyclin L1 |
| Other gene symbols | ANIA6A PRO1073 ania-6a |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | IEA | biological_process |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006396 | RNA processing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1243108051 | 0.6193499981 | 0.7199086249 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0461962396 |
| GSE13712_SHEAR | Up | 0.4095724983 |
| GSE13712_STATIC | Down | -0.0658827794 |
| GSE19018 | Down | -0.2851358169 |
| GSE19899_A1 | Down | -0.0298248332 |
| GSE19899_A2 | Up | 0.0480001413 |
| PubMed_21979375_A1 | Down | -0.1855220407 |
| PubMed_21979375_A2 | Down | -0.0128155920 |
| GSE35957 | Up | 0.4349814815 |
| GSE36640 | Down | -0.0398280377 |
| GSE54402 | Down | -0.0786132961 |
| GSE9593 | Up | 0.0973572435 |
| GSE43922 | Up | 0.0989193883 |
| GSE24585 | Up | 0.3040211045 |
| GSE37065 | Up | 0.1228353092 |
| GSE28863_A1 | Up | 0.5891035244 |
| GSE28863_A2 | Up | 0.8911493902 |
| GSE28863_A3 | Down | -0.4912706799 |
| GSE28863_A4 | Down | -0.2371467946 |
| GSE48662 | Up | 0.2388717041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-199a-5p | MIMAT0000231 | MIRT003963 | Microarray | Functional MTI (Weak) | 17875710 |
| hsa-miR-199a-5p | MIMAT0000231 | MIRT003963 | Microarray//Northern blot | Functional MTI (Weak) | 16331254 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT004383 | Microarray//Northern blot | Functional MTI (Weak) | 16331254 |
| hsa-miR-199a-3p | MIMAT0000232 | MIRT006586 | Microarray//Northern blot | Functional MTI (Weak) | 16331254 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025231 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031118 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
