HCSGD entry for ADAMTS9


1. General information

Official gene symbolADAMTS9
Entrez ID56999
Gene full nameADAM metallopeptidase with thrombospondin type 1 motif, 9
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005578Proteinaceous extracellular matrixIDAcellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0006508ProteolysisIDA IEAbiological_process
GO:0006516Glycoprotein catabolic processTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008237Metallopeptidase activityIDAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0015031Protein transportIEAbiological_process
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0031012Extracellular matrixISScellular_component
GO:0045636Positive regulation of melanocyte differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15326522170.75781748030.77996389421.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0151508362
GSE13712_SHEARDown-0.0487648209
GSE13712_STATICUp0.0448186900
GSE19018Down-0.0982349533
GSE19899_A1Up0.1228585862
GSE19899_A2Up0.4297810618
PubMed_21979375_A1Up0.9287697868
PubMed_21979375_A2Down-0.0675123931
GSE35957Up0.1103270496
GSE36640Up0.2609098348
GSE54402Down-0.1285533361
GSE9593Down-0.5000716950
GSE43922Up1.0055424632
GSE24585Down-0.0948540708
GSE37065Up0.4195875928
GSE28863_A1Down-0.0737882410
GSE28863_A2Down-0.0559056256
GSE28863_A3Up0.1992855648
GSE28863_A4Down-0.0577544917
GSE48662Down-0.0609376619

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-29a-3pMIMAT0000086MIRT005668Luciferase reporter assay//Microarray//Northern blot//qRT-PCRFunctional MTI20971881
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.