HCSGD entry for PSMB9

1. General information

Official gene symbolPSMB9
Entrez ID5698
Gene full nameproteasome (prosome, macropain) subunit, beta type, 9
Other gene symbolsLMP2 PSMB6i RING12 beta1i
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000502Proteasome complexTAScellular_component
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0004298Threonine-type endopeptidase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005839Proteasome core complexIEA ISScellular_component
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019882Antigen processing and presentationIEAbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051603Proteolysis involved in cellular protein catabolic processIEAbiological_process
GO:1990111Spermatoproteasome complexIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21278712060.00299479880.88908926980.1096329624

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3785978796
GSE13712_SHEARUp0.9642525166
GSE13712_STATICUp1.7992340520
GSE19018Down-0.0694993479
GSE19899_A1Down-0.6051994407
GSE19899_A2Down-3.1060369768
PubMed_21979375_A1Down-3.1635013620
PubMed_21979375_A2Down-1.0736851659
GSE35957Down-2.3442879258
GSE36640Up0.1167301761
GSE54402Down-0.8179668112
GSE9593Down-0.5329404171
GSE43922Down-0.9578474126
GSE24585Up0.3595276294
GSE37065Up0.8680800314
GSE28863_A1Up0.0175563554
GSE28863_A2Up0.3318721094
GSE28863_A3Down-0.1945659910
GSE28863_A4Up0.0980609989
GSE48662Down-0.2495751361

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CarfilzomibDB08889 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.