HCSGD entry for NT5M
1. General information
| Official gene symbol | NT5M |
|---|---|
| Entrez ID | 56953 |
| Gene full name | 5',3'-nucleotidase, mitochondrial |
| Other gene symbols | dNT-2 dNT2 mdN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006206 | Pyrimidine nucleobase metabolic process | TAS | biological_process |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0008252 | Nucleotidase activity | TAS | molecular_function |
| GO:0008253 | 5'-nucleotidase activity | EXP | molecular_function |
| GO:0009223 | Pyrimidine deoxyribonucleotide catabolic process | TAS | biological_process |
| GO:0016311 | Dephosphorylation | EXP TAS | biological_process |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046079 | DUMP catabolic process | IEA | biological_process |
| GO:0046135 | Pyrimidine nucleoside catabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8664433836 | 0.4688400517 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0889444909 |
| GSE13712_SHEAR | Down | -0.0861695411 |
| GSE13712_STATIC | Down | -0.2374001784 |
| GSE19018 | Down | -0.0386507138 |
| GSE19899_A1 | Down | -0.0738658187 |
| GSE19899_A2 | Down | -0.0548070081 |
| PubMed_21979375_A1 | Down | -0.2173751124 |
| PubMed_21979375_A2 | Down | -0.0983595737 |
| GSE35957 | Down | -0.2771758041 |
| GSE36640 | Up | 0.0489417200 |
| GSE54402 | Up | 0.0206036489 |
| GSE9593 | Down | -0.0462576151 |
| GSE43922 | Up | 0.0457246471 |
| GSE24585 | Down | -0.0149660135 |
| GSE37065 | Down | -0.0778804038 |
| GSE28863_A1 | Down | -0.1738259637 |
| GSE28863_A2 | Down | -0.1155230087 |
| GSE28863_A3 | Up | 0.3650917485 |
| GSE28863_A4 | Down | -0.0054377876 |
| GSE48662 | Up | 0.4075278774 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024559 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026399 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
