HCSGD entry for PRTFDC1
1. General information
| Official gene symbol | PRTFDC1 |
|---|---|
| Entrez ID | 56952 |
| Gene full name | phosphoribosyl transferase domain containing 1 |
| Other gene symbols | HHGP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000287 | Magnesium ion binding | IBA TAS | molecular_function |
| GO:0004422 | Hypoxanthine phosphoribosyltransferase activity | IDA | molecular_function |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006166 | Purine ribonucleoside salvage | IBA | biological_process |
| GO:0006168 | Adenine salvage | IBA | biological_process |
| GO:0006178 | Guanine salvage | IDA | biological_process |
| GO:0032263 | GMP salvage | IBA | biological_process |
| GO:0032264 | IMP salvage | IBA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0046038 | GMP catabolic process | IDA | biological_process |
| GO:0046100 | Hypoxanthine metabolic process | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9880400935 | 0.0003087079 | 0.9999902473 | 0.0322440476 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5552644110 |
| GSE13712_SHEAR | Down | -0.9028272935 |
| GSE13712_STATIC | Down | -0.6759534310 |
| GSE19018 | Down | -0.8699767069 |
| GSE19899_A1 | Down | -1.7810469259 |
| GSE19899_A2 | Down | -1.6451607156 |
| PubMed_21979375_A1 | Down | -1.4250545924 |
| PubMed_21979375_A2 | Down | -2.3913529028 |
| GSE35957 | Down | -0.3670723427 |
| GSE36640 | Down | -1.8296711339 |
| GSE54402 | Down | -0.8187678255 |
| GSE9593 | Down | -0.8903717358 |
| GSE43922 | Down | -1.0417029019 |
| GSE24585 | Up | 0.1003897956 |
| GSE37065 | Up | 0.1980498112 |
| GSE28863_A1 | Up | 0.1803234129 |
| GSE28863_A2 | Up | 0.4389867531 |
| GSE28863_A3 | Down | -0.4260467005 |
| GSE28863_A4 | Up | 0.1665160535 |
| GSE48662 | Down | -0.5567069088 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
