HCSGD entry for MFF
1. General information
| Official gene symbol | MFF |
|---|---|
| Entrez ID | 56947 |
| Gene full name | mitochondrial fission factor |
| Other gene symbols | C2orf33 GL004 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000266 | Mitochondrial fission | IEA ISS | biological_process |
| GO:0001836 | Release of cytochrome c from mitochondria | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IDA IEA | cellular_component |
| GO:0005777 | Peroxisome | IDA IEA | cellular_component |
| GO:0006626 | Protein targeting to mitochondrion | IMP | biological_process |
| GO:0008021 | Synaptic vesicle | IEA | cellular_component |
| GO:0008053 | Mitochondrial fusion | IMP | biological_process |
| GO:0010821 | Regulation of mitochondrion organization | IMP | biological_process |
| GO:0016559 | Peroxisome fission | IMP | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0032592 | Integral component of mitochondrial membrane | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043653 | Mitochondrial fragmentation involved in apoptotic process | IMP | biological_process |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
| GO:0070584 | Mitochondrion morphogenesis | IMP | biological_process |
| GO:0090141 | Positive regulation of mitochondrial fission | IDA | biological_process |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | IMP | biological_process |
| GO:0090314 | Positive regulation of protein targeting to membrane | IDA | biological_process |
| GO:1900063 | Regulation of peroxisome organization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9655362182 | 0.0295668364 | 0.9999902473 | 0.3257851171 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0833481080 |
| GSE13712_SHEAR | Down | -0.5256392247 |
| GSE13712_STATIC | Down | -0.0938480761 |
| GSE19018 | Down | -0.0970007573 |
| GSE19899_A1 | Down | -0.6472892343 |
| GSE19899_A2 | Down | -0.2002324515 |
| PubMed_21979375_A1 | Down | -0.1339485438 |
| PubMed_21979375_A2 | Down | -0.2696654247 |
| GSE35957 | Up | 0.0070202226 |
| GSE36640 | Down | -0.5098617416 |
| GSE54402 | Down | -0.2839691140 |
| GSE9593 | Down | -0.0800274445 |
| GSE43922 | Down | -0.3645719604 |
| GSE24585 | Down | -0.0413838380 |
| GSE37065 | Down | -0.2089473894 |
| GSE28863_A1 | Up | 0.5830685357 |
| GSE28863_A2 | Up | 0.4697233272 |
| GSE28863_A3 | Down | -0.4949983889 |
| GSE28863_A4 | Down | -0.2113046682 |
| GSE48662 | Down | -0.1977038504 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020583 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028269 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
