HCSGD entry for DUSP22
1. General information
| Official gene symbol | DUSP22 |
|---|---|
| Entrez ID | 56940 |
| Gene full name | dual specificity phosphatase 22 |
| Other gene symbols | JKAP JSP1 LMWDSP2 MKPX VHX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0000188 | Inactivation of MAPK activity | TAS | biological_process |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IBA IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | IBA IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | IBA IEA | molecular_function |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0042127 | Regulation of cell proliferation | IBA IEA | biological_process |
| GO:0046330 | Positive regulation of JNK cascade | IBA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1023781581 | 0.6810005091 | 0.6663925569 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1107925351 |
| GSE13712_SHEAR | Down | -0.4502023699 |
| GSE13712_STATIC | Down | -0.2604556633 |
| GSE19018 | Down | -0.2224815886 |
| GSE19899_A1 | Up | 0.0095930639 |
| GSE19899_A2 | Up | 0.4560037571 |
| PubMed_21979375_A1 | Up | 1.6097432770 |
| PubMed_21979375_A2 | Up | 0.2784166587 |
| GSE35957 | Up | 0.3598778882 |
| GSE36640 | Up | 0.9615645784 |
| GSE54402 | Down | -0.5101780746 |
| GSE9593 | Up | 0.3735256710 |
| GSE43922 | Up | 0.0523956904 |
| GSE24585 | Up | 0.0534055658 |
| GSE37065 | Up | 0.0208277588 |
| GSE28863_A1 | Up | 0.2175227997 |
| GSE28863_A2 | Up | 0.4559018897 |
| GSE28863_A3 | Up | 0.0314785257 |
| GSE28863_A4 | Down | -0.0068283390 |
| GSE48662 | Up | 0.0396081007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019217 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030306 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
