HCSGD entry for MCCC1

1. General information

Official gene symbolMCCC1
Entrez ID56922
Gene full namemethylcrotonoyl-CoA carboxylase 1 (alpha)
Other gene symbolsMCC-B MCCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004075Biotin carboxylase activityIEAmolecular_function
GO:0004485Methylcrotonoyl-CoA carboxylase activityIDA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixNAS TAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006552Leucine catabolic processIEA NASbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006768Biotin metabolic processNAS TASbiological_process
GO:0009083Branched-chain amino acid catabolic processTASbiological_process
GO:0009374Biotin bindingNASmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76208609860.02963443640.99999024730.3257974948

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4426263416
GSE13712_SHEARDown-0.9703035190
GSE13712_STATICDown-0.1225428376
GSE19018Up0.3896915499
GSE19899_A1Down-0.7155404709
GSE19899_A2Down-0.3146211463
PubMed_21979375_A1Down-0.8638590521
PubMed_21979375_A2Down-0.2975403597
GSE35957Down-0.4516915073
GSE36640Up0.7461109353
GSE54402Up0.0811471467
GSE9593Down-0.2124166962
GSE43922Down-0.6724139627
GSE24585Up0.4953456890
GSE37065Down-0.0911989484
GSE28863_A1Down-0.0798721929
GSE28863_A2Down-0.0855034551
GSE28863_A3Down-0.5231245769
GSE28863_A4Down-0.1713193887
GSE48662Down-0.1899904251

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.