HCSGD entry for AGPAT3


1. General information

Official gene symbolAGPAT3
Entrez ID56894
Gene full name1-acylglycerol-3-phosphate O-acyltransferase 3
Other gene symbolsLPAAT-GAMMA1 LPAAT3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00038411-acylglycerol-3-phosphate O-acyltransferase activityNASmolecular_function
GO:0005635Nuclear envelopeIEAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006654Phosphatidic acid biosynthetic processTASbiological_process
GO:0008654Phospholipid biosynthetic processNASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016024CDP-diacylglycerol biosynthetic processIEAbiological_process
GO:0016746Transferase activity, transferring acyl groupsIEAmolecular_function
GO:0019432Triglyceride biosynthetic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18447259600.59161192960.83942067061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1286219883
GSE13712_SHEARUp0.1841583805
GSE13712_STATICUp0.1194916644
GSE19018Down-0.0614990581
GSE19899_A1Down-0.2292484484
GSE19899_A2Up0.4087835598
PubMed_21979375_A1Down-0.0005641001
PubMed_21979375_A2Up0.6731339758
GSE35957Down-0.0675698981
GSE36640Up0.3772218262
GSE54402Down-0.4500639842
GSE9593Up0.2759641233
GSE43922Up0.0016368530
GSE24585Down-0.0856353385
GSE37065Down-0.0185309242
GSE28863_A1Up0.5814032776
GSE28863_A2Up0.6241833993
GSE28863_A3Down-0.0291718447
GSE28863_A4Up0.0667130610
GSE48662Down-0.3357648346

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT016086SequencingFunctional MTI (Weak)20371350
hsa-miR-744-5pMIMAT0004945MIRT016086CLASHFunctional MTI (Weak)23622248
hsa-miR-335-5pMIMAT0000765MIRT017029MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029038SequencingFunctional MTI (Weak)20371350
hsa-miR-24-3pMIMAT0000080MIRT030467MicroarrayFunctional MTI (Weak)19748357
hsa-miR-24-3pMIMAT0000080MIRT030467SequencingFunctional MTI (Weak)20371350
hsa-miR-18a-3pMIMAT0002891MIRT040936CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045627CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048576CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.