HCSGD entry for ZC3HAV1
1. General information
| Official gene symbol | ZC3HAV1 |
|---|---|
| Entrez ID | 56829 |
| Gene full name | zinc finger CCCH-type, antiviral 1 |
| Other gene symbols | ARTD13 FLB6421 PARP13 ZAP ZC3H2 ZC3HDC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003950 | NAD+ ADP-ribosyltransferase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0009615 | Response to virus | IDA | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | IEA | biological_process |
| GO:0032727 | Positive regulation of interferon-alpha production | IDA | biological_process |
| GO:0032728 | Positive regulation of interferon-beta production | IDA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0061014 | Positive regulation of mRNA catabolic process | IDA | biological_process |
| GO:0071360 | Cellular response to exogenous dsRNA | IEA | biological_process |
| GO:1900246 | Positive regulation of RIG-I signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1295057787 | 0.0932564948 | 0.7307013076 | 0.5817976298 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3113837666 |
| GSE13712_SHEAR | Up | 0.7230350785 |
| GSE13712_STATIC | Up | 0.8446061980 |
| GSE19018 | Down | -0.0867800244 |
| GSE19899_A1 | Down | -0.4642738008 |
| GSE19899_A2 | Down | -0.5288616961 |
| PubMed_21979375_A1 | Down | -0.4877383704 |
| PubMed_21979375_A2 | Down | -0.4477180265 |
| GSE35957 | Down | -0.9119805532 |
| GSE36640 | Up | 0.0223798463 |
| GSE54402 | Down | -0.5474561115 |
| GSE9593 | Down | -0.1097575833 |
| GSE43922 | Down | -0.2659731350 |
| GSE24585 | Up | 0.2080832008 |
| GSE37065 | Up | 0.5576634990 |
| GSE28863_A1 | Up | 0.8070672852 |
| GSE28863_A2 | Up | 1.4270178044 |
| GSE28863_A3 | Down | -0.2548235394 |
| GSE28863_A4 | Down | -0.2705984541 |
| GSE48662 | Down | -0.2092216128 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019853 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039904 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049602 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052130 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
