HCSGD entry for BCCIP
1. General information
| Official gene symbol | BCCIP |
|---|---|
| Entrez ID | 56647 |
| Gene full name | BRCA2 and CDKN1A interacting protein |
| Other gene symbols | TOK-1 TOK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA TAS | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0019207 | Kinase regulator activity | IDA | molecular_function |
| GO:0019908 | Nuclear cyclin-dependent protein kinase holoenzyme complex | IDA | cellular_component |
| GO:0061101 | Neuroendocrine cell differentiation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8656085901 | 0.0194784849 | 0.9999902473 | 0.2725641680 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3466362871 |
| GSE13712_SHEAR | Up | 0.3088053489 |
| GSE13712_STATIC | Up | 0.2712789439 |
| GSE19018 | Down | -0.7438278066 |
| GSE19899_A1 | Down | -0.0549592457 |
| GSE19899_A2 | Down | -0.4245944876 |
| PubMed_21979375_A1 | Down | -0.4494573929 |
| PubMed_21979375_A2 | Down | -0.7314452426 |
| GSE35957 | Down | -0.5998690698 |
| GSE36640 | Down | -0.9495636320 |
| GSE54402 | Up | 0.3994691815 |
| GSE9593 | Down | -0.8849605642 |
| GSE43922 | Up | 0.0028602249 |
| GSE24585 | Down | -0.5433599972 |
| GSE37065 | Down | -0.0540926523 |
| GSE28863_A1 | Up | 0.1035751331 |
| GSE28863_A2 | Down | -0.1586594666 |
| GSE28863_A3 | Down | -0.2551506982 |
| GSE28863_A4 | Up | 0.1703027829 |
| GSE48662 | Down | -0.6585781595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022455 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025700 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031532 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038174 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT048007 | CLASH | Functional MTI (Weak) | 23622248 |
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