HCSGD entry for BCCIP


1. General information

Official gene symbolBCCIP
Entrez ID56647
Gene full nameBRCA2 and CDKN1A interacting protein
Other gene symbolsTOK-1 TOK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityIDAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEA TAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0019207Kinase regulator activityIDAmolecular_function
GO:0019908Nuclear cyclin-dependent protein kinase holoenzyme complexIDAcellular_component
GO:0061101Neuroendocrine cell differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86560859010.01947848490.99999024730.2725641680

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3466362871
GSE13712_SHEARUp0.3088053489
GSE13712_STATICUp0.2712789439
GSE19018Down-0.7438278066
GSE19899_A1Down-0.0549592457
GSE19899_A2Down-0.4245944876
PubMed_21979375_A1Down-0.4494573929
PubMed_21979375_A2Down-0.7314452426
GSE35957Down-0.5998690698
GSE36640Down-0.9495636320
GSE54402Up0.3994691815
GSE9593Down-0.8849605642
GSE43922Up0.0028602249
GSE24585Down-0.5433599972
GSE37065Down-0.0540926523
GSE28863_A1Up0.1035751331
GSE28863_A2Down-0.1586594666
GSE28863_A3Down-0.2551506982
GSE28863_A4Up0.1703027829
GSE48662Down-0.6585781595

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022455Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-7-5pMIMAT0000252MIRT025700MicroarrayFunctional MTI (Weak)19073608
hsa-miR-16-5pMIMAT0000069MIRT031532ProteomicsFunctional MTI (Weak)18668040
hsa-miR-423-5pMIMAT0004748MIRT038174CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT048007CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.