HCSGD entry for PRPSAP1
1. General information
| Official gene symbol | PRPSAP1 |
|---|---|
| Entrez ID | 5635 |
| Gene full name | phosphoribosyl pyrophosphate synthetase-associated protein 1 |
| Other gene symbols | PAP39 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0002189 | Ribose phosphate diphosphokinase complex | IEA | cellular_component |
| GO:0004749 | Ribose phosphate diphosphokinase activity | IEA | molecular_function |
| GO:0004857 | Enzyme inhibitor activity | TAS | molecular_function |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0009165 | Nucleotide biosynthetic process | IEA | biological_process |
| GO:0019900 | Kinase binding | IEA | molecular_function |
| GO:0030234 | Enzyme regulator activity | IEA | molecular_function |
| GO:0033673 | Negative regulation of kinase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5303980700 | 0.1527988260 | 0.9999902473 | 0.7548951952 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3199895108 |
| GSE13712_SHEAR | Up | 0.5896806866 |
| GSE13712_STATIC | Up | 0.1479390274 |
| GSE19018 | Up | 0.4735204269 |
| GSE19899_A1 | Down | -0.1218455241 |
| GSE19899_A2 | Up | 0.0069879686 |
| PubMed_21979375_A1 | Down | -0.6366972448 |
| PubMed_21979375_A2 | Down | -0.2871740060 |
| GSE35957 | Down | -0.4709019124 |
| GSE36640 | Down | -0.4319763290 |
| GSE54402 | Up | 0.0127007005 |
| GSE9593 | Down | -0.1936598180 |
| GSE43922 | Up | 0.0532385403 |
| GSE24585 | Up | 0.8110169541 |
| GSE37065 | Down | -0.1968286096 |
| GSE28863_A1 | Down | -0.0364125950 |
| GSE28863_A2 | Up | 0.2951980014 |
| GSE28863_A3 | Down | -0.4454452604 |
| GSE28863_A4 | Down | -0.0121064434 |
| GSE48662 | Down | -0.3735373671 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021127 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031682 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031682 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039657 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
