HCSGD entry for PRMT8

1. General information

Official gene symbolPRMT8
Entrez ID56341
Gene full nameprotein arginine methyltransferase 8
Other gene symbolsHRMT1L3 HRMT1L4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0008469Histone-arginine N-methyltransferase activityIDAmolecular_function
GO:0008757S-adenosylmethionine-dependent methyltransferase activityIDAmolecular_function
GO:0016571Histone methylationIDAbiological_process
GO:0018216Peptidyl-arginine methylationIDAbiological_process
GO:0019919Peptidyl-arginine methylation, to asymmetrical-dimethyl arginineIDAbiological_process
GO:0034969Histone arginine methylationIDAbiological_process
GO:0035241Protein-arginine omega-N monomethyltransferase activityIDAmolecular_function
GO:0035242Protein-arginine omega-N asymmetric methyltransferase activityIDAmolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043393Regulation of protein bindingTASbiological_process
GO:0046982Protein heterodimerization activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79919768250.83671245770.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0703156567
GSE13712_SHEARDown-0.0058628947
GSE13712_STATICDown-0.0922808299
GSE19018Down-0.0679551422
GSE19899_A1Up0.0033270390
GSE19899_A2Up0.2620973470
PubMed_21979375_A1Down-0.1432085678
PubMed_21979375_A2Down-0.0701722884
GSE35957Up0.1808529301
GSE36640Up0.1501054386
GSE54402Down-0.0735503576
GSE9593Up0.1003184947
GSE43922Up0.0112018850
GSE24585Up0.1188349873
GSE37065Up0.0051789360
GSE28863_A1Down-0.0176984096
GSE28863_A2Up0.0247646271
GSE28863_A3Up0.1541107650
GSE28863_A4Up0.0764590744
GSE48662Down-0.0543910559

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-330-3pMIMAT0000751MIRT043830CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.