HCSGD entry for IRGC
1. General information
| Official gene symbol | IRGC |
|---|---|
| Entrez ID | 56269 |
| Gene full name | immunity-related GTPase family, cinema |
| Other gene symbols | CINEMA IFGGE IRGC1 Iigp5 R30953_1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016817 | Hydrolase activity, acting on acid anhydrides | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6582002014 | 0.7111874283 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1026288323 |
| GSE13712_SHEAR | Up | 0.0782927994 |
| GSE13712_STATIC | Down | -0.1023411902 |
| GSE19018 | Up | 0.0074843838 |
| GSE19899_A1 | Up | 0.0352644404 |
| GSE19899_A2 | Up | 0.2186053517 |
| PubMed_21979375_A1 | Up | 0.4253747090 |
| PubMed_21979375_A2 | Down | -0.1388745091 |
| GSE35957 | Up | 0.0580786776 |
| GSE36640 | Up | 0.0175383786 |
| GSE54402 | Up | 0.0404519547 |
| GSE9593 | Up | 0.0383767609 |
| GSE43922 | Up | 0.0138248351 |
| GSE24585 | Down | -0.1403819570 |
| GSE37065 | Down | -0.0390778928 |
| GSE28863_A1 | Down | -0.0346757509 |
| GSE28863_A2 | Down | -0.0612311743 |
| GSE28863_A3 | Up | 0.3742906817 |
| GSE28863_A4 | Up | 0.0559173360 |
| GSE48662 | Down | -0.1064353691 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-(N-Morpholino)-Ethanesulfonic Acid | DB03814 | EXPT02154 |
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029888 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
