HCSGD entry for CRTAM
1. General information
| Official gene symbol | CRTAM |
|---|---|
| Entrez ID | 56253 |
| Gene full name | cytotoxic and regulatory T cell molecule |
| Other gene symbols | CD355 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001913 | T cell mediated cytotoxicity | IDA | biological_process |
| GO:0002355 | Detection of tumor cell | IDA | biological_process |
| GO:0002860 | Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | IDA | biological_process |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0008037 | Cell recognition | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0045954 | Positive regulation of natural killer cell mediated cytotoxicity | IDA | biological_process |
| GO:0050715 | Positive regulation of cytokine secretion | IDA | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
| GO:0050798 | Activated T cell proliferation | IDA | biological_process |
| GO:0051606 | Detection of stimulus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1195718818 | 0.9557210174 | 0.7083600675 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2562044796 |
| GSE13712_SHEAR | Up | 0.0982887479 |
| GSE13712_STATIC | Down | -0.1948243912 |
| GSE19018 | Down | -0.1302069421 |
| GSE19899_A1 | Up | 0.5085134589 |
| GSE19899_A2 | Up | 0.1814390105 |
| PubMed_21979375_A1 | Up | 0.3379184335 |
| PubMed_21979375_A2 | Up | 0.1499978607 |
| GSE35957 | Down | -0.0642932123 |
| GSE36640 | Up | 0.2171692494 |
| GSE54402 | Up | 0.0971801349 |
| GSE9593 | Up | 0.4611113435 |
| GSE43922 | Up | 0.0100817171 |
| GSE24585 | Down | -0.0808251647 |
| GSE37065 | Up | 0.3761645636 |
| GSE28863_A1 | Up | 0.1244868414 |
| GSE28863_A2 | Up | 0.0422368048 |
| GSE28863_A3 | Up | 0.1927153830 |
| GSE28863_A4 | Down | -0.0254282058 |
| GSE48662 | Up | 0.1192302358 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018919 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030104 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
