HCSGD entry for NKRF
1. General information
| Official gene symbol | NKRF |
|---|---|
| Entrez ID | 55922 |
| Gene full name | NFKB repressing factor |
| Other gene symbols | ITBA4 NRF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0240837962 | 0.7968368907 | 0.3679103889 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0714200614 |
| GSE13712_SHEAR | Up | 0.2082378367 |
| GSE13712_STATIC | Up | 0.1070354167 |
| GSE19018 | Down | -0.3129303050 |
| GSE19899_A1 | Up | 0.3067982832 |
| GSE19899_A2 | Up | 0.8507644060 |
| PubMed_21979375_A1 | Up | 1.3990525775 |
| PubMed_21979375_A2 | Up | 1.6272551599 |
| GSE35957 | Down | -0.1650922739 |
| GSE36640 | Down | -0.2708699305 |
| GSE54402 | Up | 0.4794096287 |
| GSE9593 | Down | -0.2366280779 |
| GSE43922 | Up | 0.8392807924 |
| GSE24585 | Down | -0.7325128335 |
| GSE37065 | Down | -0.0366934850 |
| GSE28863_A1 | Up | 0.2578716962 |
| GSE28863_A2 | Up | 0.4924723549 |
| GSE28863_A3 | Down | -0.0245357702 |
| GSE28863_A4 | Up | 0.0817718313 |
| GSE48662 | Down | -0.0946927144 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-301a-3p | MIMAT0000688 | MIRT004113 | Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 21113131 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016042 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019542 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024508 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026214 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-326 | MIMAT0000756 | MIRT043642 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046801 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
