HCSGD entry for UNC45A
1. General information
| Official gene symbol | UNC45A |
|---|---|
| Entrez ID | 55898 |
| Gene full name | unc-45 homolog A (C. elegans) |
| Other gene symbols | GC-UNC45 GCUNC-45 GCUNC45 IRO039700 SMAP-1 SMAP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007517 | Muscle organ development | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051879 | Hsp90 protein binding | IEA | molecular_function |
| GO:0061077 | Chaperone-mediated protein folding | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7756416626 | 0.5478526006 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0124753421 |
| GSE13712_SHEAR | Up | 0.1510108338 |
| GSE13712_STATIC | Down | -0.0422576143 |
| GSE19018 | Up | 0.1588508710 |
| GSE19899_A1 | Down | -0.0227649300 |
| GSE19899_A2 | Up | 0.2391885691 |
| PubMed_21979375_A1 | Up | 0.0720551605 |
| PubMed_21979375_A2 | Up | 0.3283169580 |
| GSE35957 | Down | -0.0818330851 |
| GSE36640 | Up | 0.0332707567 |
| GSE54402 | Down | -0.0640366877 |
| GSE9593 | Down | -0.1856712749 |
| GSE43922 | Up | 0.0103093389 |
| GSE24585 | Down | -0.0818968461 |
| GSE37065 | Down | -0.1495405741 |
| GSE28863_A1 | Down | -0.1997858655 |
| GSE28863_A2 | Down | -0.0916964162 |
| GSE28863_A3 | Down | -0.1367596367 |
| GSE28863_A4 | Down | -0.1337148837 |
| GSE48662 | Up | 0.2947319021 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023949 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-940 | MIMAT0004983 | MIRT036617 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038832 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044266 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045768 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046354 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048871 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
