HCSGD entry for BRK1

1. General information

Official gene symbolBRK1
Entrez ID55845
Gene full nameBRICK1, SCAR/WAVE actin-nucleating complex subunit
Other gene symbolsC3orf10 MDS027 hHBrk1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0030036Actin cytoskeleton organizationIEAbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048870Cell motilityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09833246840.13653853960.65408362400.7118437116

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2779696396
GSE13712_SHEARDown-0.3201355337
GSE13712_STATICDown-0.0600983400
GSE19018Up0.6072995422
GSE19899_A1Up0.3378633761
GSE19899_A2Up0.3068150446
PubMed_21979375_A1Up0.2181771559
PubMed_21979375_A2Up0.2446923076
GSE35957Up0.3533099921
GSE36640Up0.6369682552
GSE54402Up0.4817144353
GSE9593Up0.0774806803
GSE43922Up0.0271502352
GSE24585Up0.0863439214
GSE37065Up0.0051668785
GSE28863_A1Down-0.5351832563
GSE28863_A2Down-1.0522253683
GSE28863_A3Down-0.8664117177
GSE28863_A4Down-0.4934995905
GSE48662Up0.0681800429

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.