HCSGD entry for CENPJ
1. General information
| Official gene symbol | CENPJ |
|---|---|
| Entrez ID | 55835 |
| Gene full name | centromere protein J |
| Other gene symbols | BM032 CENP-J CPAP LAP LIP1 MCPH6 SASS4 SCKL4 Sas-4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005814 | Centriole | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007020 | Microtubule nucleation | TAS | biological_process |
| GO:0007099 | Centriole replication | IMP | biological_process |
| GO:0008275 | Gamma-tubulin small complex | NAS | cellular_component |
| GO:0015631 | Tubulin binding | IDA | molecular_function |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0046599 | Regulation of centriole replication | IMP | biological_process |
| GO:0046785 | Microtubule polymerization | IMP | biological_process |
| GO:0051301 | Cell division | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9982373618 | 0.0004953003 | 0.9999902473 | 0.0411066038 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0662358159 |
| GSE13712_SHEAR | Down | -0.0233271451 |
| GSE13712_STATIC | Down | -0.4150726480 |
| GSE19018 | Down | -0.1706920633 |
| GSE19899_A1 | Down | -0.2259177070 |
| GSE19899_A2 | Down | -2.1066499938 |
| PubMed_21979375_A1 | Down | -1.1056315655 |
| PubMed_21979375_A2 | Down | -1.1324298162 |
| GSE35957 | Down | -1.0861339151 |
| GSE36640 | Down | -2.5840463418 |
| GSE54402 | Down | -0.3582047447 |
| GSE9593 | Down | -0.6107687166 |
| GSE43922 | Down | -0.7894756135 |
| GSE24585 | Down | -0.1325402309 |
| GSE37065 | Down | -0.1530852411 |
| GSE28863_A1 | Down | -0.7593969385 |
| GSE28863_A2 | Down | -0.5802508587 |
| GSE28863_A3 | Down | -0.3519993765 |
| GSE28863_A4 | Up | 0.1227408243 |
| GSE48662 | Down | -1.1138941624 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000828 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000829 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016265 | Microarray | Functional MTI (Weak) | 20304954 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
