HCSGD entry for TRERF1
1. General information
| Official gene symbol | TRERF1 |
|---|---|
| Entrez ID | 55809 |
| Gene full name | transcriptional regulating factor 1 |
| Other gene symbols | BCAR2 HSA277276 RAPA RP1-139D8.5 TReP-132 dJ139D8.5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity | NAS | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0006694 | Steroid biosynthetic process | NAS | biological_process |
| GO:0006707 | Cholesterol catabolic process | NAS | biological_process |
| GO:0007275 | Multicellular organismal development | NAS | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0008301 | DNA binding, bending | NAS | molecular_function |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | NAS | molecular_function |
| GO:0042592 | Homeostatic process | NAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046885 | Regulation of hormone biosynthetic process | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5625381862 | 0.0205431367 | 0.9999902473 | 0.2770485143 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2403488266 |
| GSE13712_SHEAR | Down | -0.3791942601 |
| GSE13712_STATIC | Up | 0.2967544256 |
| GSE19018 | Down | -0.0893300374 |
| GSE19899_A1 | Down | -0.1225432920 |
| GSE19899_A2 | Down | -1.0624735668 |
| PubMed_21979375_A1 | Down | -1.8372294528 |
| PubMed_21979375_A2 | Down | -0.6462448134 |
| GSE35957 | Down | -0.4418046562 |
| GSE36640 | Down | -0.7447139031 |
| GSE54402 | Down | -0.6163221459 |
| GSE9593 | Up | 0.1276523846 |
| GSE43922 | Down | -0.7920750656 |
| GSE24585 | Up | 0.5349249472 |
| GSE37065 | Up | 0.2666435094 |
| GSE28863_A1 | Up | 1.0085208876 |
| GSE28863_A2 | Up | 0.4340602784 |
| GSE28863_A3 | Down | -0.1281635161 |
| GSE28863_A4 | Up | 0.0532690943 |
| GSE48662 | Down | -0.3366217047 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018109 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023419 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027377 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043205 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043712 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
