HCSGD entry for FGD6
1. General information
| Official gene symbol | FGD6 |
|---|---|
| Entrez ID | 55785 |
| Gene full name | FYVE, RhoGEF and PH domain containing 6 |
| Other gene symbols | ZFYVE24 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | ISS | cellular_component |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | ISS | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0007010 | Cytoskeleton organization | ISS | biological_process |
| GO:0008360 | Regulation of cell shape | ISS | biological_process |
| GO:0030027 | Lamellipodium | ISS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | ISS | biological_process |
| GO:0031267 | Small GTPase binding | ISS | molecular_function |
| GO:0043088 | Regulation of Cdc42 GTPase activity | ISS | biological_process |
| GO:0046847 | Filopodium assembly | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6933324874 | 0.2131849132 | 0.9999902473 | 0.8915733397 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0906113410 |
| GSE13712_SHEAR | Up | 0.3710903803 |
| GSE13712_STATIC | Up | 0.1611290860 |
| GSE19018 | Down | -0.0340333583 |
| GSE19899_A1 | Down | -0.1084169573 |
| GSE19899_A2 | Down | -0.3535993211 |
| PubMed_21979375_A1 | Down | -0.2539553622 |
| PubMed_21979375_A2 | Down | -0.3325948819 |
| GSE35957 | Up | 0.1595427793 |
| GSE36640 | Up | 0.0496453526 |
| GSE54402 | Down | -0.0886358820 |
| GSE9593 | Down | -0.0477530573 |
| GSE43922 | Down | -0.3831056651 |
| GSE24585 | Up | 0.2101233827 |
| GSE37065 | Up | 0.2383114492 |
| GSE28863_A1 | Up | 0.0638022806 |
| GSE28863_A2 | Down | -0.0800155117 |
| GSE28863_A3 | Down | -0.5760909914 |
| GSE28863_A4 | Up | 0.1881595299 |
| GSE48662 | Down | -0.0835736775 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018984 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027861 | Microarray | Functional MTI (Weak) | 19088304 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
