HCSGD entry for NGLY1
1. General information
| Official gene symbol | NGLY1 |
|---|---|
| Entrez ID | 55768 |
| Gene full name | N-glycanase 1 |
| Other gene symbols | PNG1 PNGase |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000224 | Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006516 | Glycoprotein catabolic process | IDA IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8717184567 | 0.2620450781 | 0.9999902473 | 0.9832189655 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1549168049 |
| GSE13712_SHEAR | Down | -0.0268781959 |
| GSE13712_STATIC | Up | 0.0880908826 |
| GSE19018 | Up | 0.0208859365 |
| GSE19899_A1 | Up | 0.1727171958 |
| GSE19899_A2 | Up | 0.0422157160 |
| PubMed_21979375_A1 | Up | 0.3100620021 |
| PubMed_21979375_A2 | Down | -0.0361203990 |
| GSE35957 | Down | -0.5519169793 |
| GSE36640 | Down | -0.0157256058 |
| GSE54402 | Up | 0.1635408769 |
| GSE9593 | Up | 0.0215232148 |
| GSE43922 | Up | 0.0414333743 |
| GSE24585 | Up | 0.1501464997 |
| GSE37065 | Down | -0.0180439975 |
| GSE28863_A1 | Down | -0.0819292361 |
| GSE28863_A2 | Down | -0.0022905452 |
| GSE28863_A3 | Down | -0.8886497089 |
| GSE28863_A4 | Down | -0.2101998074 |
| GSE48662 | Down | -0.2556711816 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT045306 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
